Synthesis of a C (7)-hydroxylated analog of the psychotropic preparation fluoracizine

AL ékonomov, AN Gritsenko, AE Vasil'ev

Index: Ekonomov,A.L. et al. Pharmaceutical Chemistry Journal, 1977 , vol. 11, # 10 p. 1371 - 1376 Khimiko-Farmatsevticheskii Zhurnal, 1977 , vol. 11, # 10 p. 76 - 82

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Abstract

The first of them was the shorter, comprising two stages. On oxidizing 2-trlfluoro~ methylphenothiazine (IX)[i0] with ferric chloride in an aqueous organic medium a complex mixture of substances was obtained from which 2-trifluoromethylphenothiaz-7-one (X) was