Friedel-Crafts Isopropylation of Acetophenone, Methyl Benzoate and Benzoic Acid1

BN Campbell Jr, EC Spaeth

Index: Campbell; Spaeth Journal of the American Chemical Society, 1959 , vol. 81, p. 5933,5934

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Citation Number: 8

Abstract

The isopropylation of acetophenone, methyl benzoate and benzoic acid was studied to determine the composition of the resulting monoalkylated products. Although generally the yields were low, it was noted that with all the experimental conditions used the products were largely or entirely composed of the meta isomers. In most cases tliese isomers constituted 95% or more of the products. This is a far greater selectivity than has been ...