Journal of the American Chemical Society

Researches on Quinazolines. XLIII. The Synthesis of a Quinazoline Derivative Structurally Analogous to Cusparine

D Papa, MT Bogert

Index: Papa; Bogert Journal of the American Chemical Society, 1936 , vol. 58, p. 1701

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Citation Number: 2

Abstract

Conclusions The Wurtz reaction can be interrupted at the intermediate organo-metallic stage if the alkyl halide is added to excess sodium at low or moderate temperatures. The reaction has been studied in some detail with n-amyl chloride and has been tested in a preliminary way with a number of other organic halides. In the case of n-amyl chloride, caproic and butylmalonic acids were obtained upon carbonation. The yield of combined acids in one ...