Synlett

A New General Approach for the Synthesis of 2-Substituted-3H-indol-3-one N-Oxide Derivatives

VB Génisson, AV Bouniol, F Nepveu

Index: Genisson, Vania Bernardes; Bouniol, Anne-Valerie; Nepveu, Francoise Synlett, 2001 , # 5 p. 700 - 702

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Citation Number: 10

Abstract

Abstract: 2-aryl (phenyl, 1, 3-benzodioxolyl) and 2-alkyl (ethyl, sec-butyl)-3H-indol-3-one N- oxides were synthesized by a new general method involving a reductive intramolecular cyclization reaction of ortho-diketo nitrobenzene derivatives. Key words: isatogens, nitrone, a-diketone, intramolecular cyclization, oxidation