Methylation of heterocyclic compounds containing NH, SH and/or OH groups by means of N, N-dimethylformamide dimethyl acetal

B Stanovnik, M Tisler, A Hribar, GB Barlin…

Index: Stanovnik, Branko; Tisler, Miha; Hribar, Alenka; Barlin, Gordon B.; Brown, Desmond J. Australian Journal of Chemistry, 1981 , vol. 34, # 8 p. 1729 - 1738

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Citation Number: 37

Abstract

Abstract Methylations of heterocyclic systems, such as benzimidazole, naphth [2, 3-c] imidazole, imidazo [4, 5-c]-pyridine, purine, pyridine, pyrimidine, pyridazine and s-triazolo [4, 3-b] pyridazine, which bore SH, NH and/or OH groups, were carried out with dimethylformamide dimethyl acetal to give the corresponding S-, N-and/or O-methyl derivatives in high yields. Selective methylation of some compounds containing both SH ...