Palladium-catalyzed decarboxylative allylic alkylation of allylic acetates with. beta.-keto acids

…, M Okada, S Nishi, T Saegusa

Index: Tsuda, Tetsuo; Okada, Masahiro; Nishi, Sei-ichi; Saegusa, Takeo Journal of Organic Chemistry, 1986 , vol. 51, # 4 p. 421 - 426

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Citation Number: 41

Abstract

In the presence of 5 mol'% of Pd (PPhJ4,@-keto acids were reacted with allylic acetates in benzene or tetrahydrofuran (THF) at room temperature to produce a-allylic ketones with quantitative evolution of COz (eq 2). a-Allylic ketones are the allylic alkylation products of allylic acetates by p-keto acids.@-Keto acids employed (1)(a) Trost, BM Acc. Chem. Res. 1980, 13, 385.(b) Tsuji, J.