Abstract The α-ureidoalkylation of imidazolidine-2, 4-dione, urea, carboxylic acid amides, and sulfonamides has been studied using 1, 3-bis (hydroxymethyl)-imidazolidin-2-one as ureidoalkylating agent. Methods have been developed for the synthesis of 1, 3-bis (2, 4-