The work reported in this communication is the synthesis of some 3, 4-dioxythiophenes in an attempt to obtain the compound represented by V. It was thought that such a cornpound might have interesting effects on the growth of organisms requiring biotin. Karrer2 has reported the synthesis of some 3, 4-dioxythiophenes of similar structure by an entirely different procedure. Because of the press of. war research, the steps from compound IV to ...