Inhibition on human liver cytochrome P450 3A4 by constituents of fennel (Foeniculum vulgare): identification and characterization of a mechanism-based inactivator

SFH Zaidi, S Kadota, Y Tezuka

Index: Foye, William O.; Wang, Xiping; Hongfu, Wang Medicinal Chemistry Research, 1997 , vol. 7, # 3 p. 180 - 191

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Citation Number: 26

Abstract

... In the previous investigation on the mechanism-based inhibition of 30 Indonesian medicinal plants, the methanol extract of ... preparative TCL with n-hexane/EtOAc or CH 3 CN/MeOH/H 2 O gave 13 ... F. vulgare) is a popular spice and is also used as a traditional medicine in Asia ...