European Journal of Organic Chemistry 2017-10-09

Tandem Ring Opening/Cyclization of trans-2-Aryl-3-nitrocyclopropane-1,1-dicarboxylates with 2-Aminopyridines: Access to Pyrido[1,2-a]pyrimidin-4-one Derivatives

Subramani Selvi, Kannupal Srinivasan

Index: 10.1002/ejoc.201700765

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Abstract

trans-2-Aryl-3-nitrocyclopropane-1,1-dicarboxylates undergo tandem ring opening/cyclization with 2-aminopyridines in water to afford pyrido[1,2-a]pyrimidin-4-one derivatives.