Chinese Chemical Letters

A mild and highly efficient one-pot three-component reaction for carbon–sulfur bond formation catalyzed by potassium tert-butoxide

B Movassagh, A Rakhshani

Index: Movassagh, Barahman; Rakhshani, Amir Chinese Chemical Letters, 2011 , vol. 22, # 10 p. 1179 - 1182

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Citation Number: 7

Abstract

Potassium tert-butoxide has been found to be a highly efficient catalyst for one-pot, three- component reaction of aryl aldehydes, acetophenones, and thiols via Claisen– Schmidt/Michael addition reactions for the synthesis of thia-Michael adducts in high yields. The reactions are best carried out in tert-butyl alcohol at room temperature.