Abstract In an attempt to discover new potent inhibitors for Mycobacterium tuberculosis (Mtb), a series of 2-(2-hydrazinyl) thiazole derivatives with a wide range of substitutions at 2-, 4-and 5-positions were designed by considering Lipinski rule. The designed compounds were synthesized, characterized and evaluated for their inhibitory potential against Mtb, H 37 Rv, by in vitro assay. The compounds, ethyl-4-methyl-2-[(E)-2-[1-(pyridin-2-yl) ...
![[(3-hydroxy-4-methoxyphenyl)methylideneamino]thiourea Structure](https://image.chemsrc.com/caspic/357/14453-26-0.png)
![Hydrazinecarbothioamide,2-[(3-ethoxy-4-hydroxyphenyl)methylene]- Structure](https://image.chemsrc.com/caspic/440/6324-85-2.png)