Highly Potent 1, 4-Benzothiazine Derivatives as KATP-Channel Openers 1

…, S Sabatini, E Filipponi, L Testai, R Spogli…

Index: Buckle, Derek R.; Houge-Frydrych, Catherine S. V.; Pinto, Ivan L.; Smith, David G.; Tedder, John M. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1991 , # 1 p. 63 - 70

Full Text: HTML

Citation Number: 39

Abstract

... of potassium ions from the cell with a simultaneous transmembrane hyperpolarization that restricts calcium entry through voltage-dependent (L-type) calcium ... compd, X, R 4, R 6, E max b ± SEM, c %, pIC 50 d ± SEM c. ... a −d,g,j See corresponding footnotes in Table 1. e See ref 29a ...