1 !xi_" HUANG-MINLON AND RUSSELL H. PETTEBONE ... [COS PRIBUTION FROM THE RESEARCH LABORATORIES, MERCK & CO., INC.] A Further Study on the Reduction of Steroid Semicarbazones ... BY HUANG-MINLON AND RUSSELL H. PETTEBONE ... A product isolated from the reaction mixture of cortisone acetate 3-semicarbazone after LiBH4 reduction followed by acetylation and regeneration has been proved to be 4-pregnane-11,17,20,21-tetrol-3-one-21-acetate