Nickel??Catalyzed Cross??Coupling of Aryl Bromides with Tertiary Grignard Reagents Utilizing Donor??Functionalized N??Heterocyclic Carbenes (NHCs)

…, T Droege, C Wang, F Glorius

Index: Lohre, Claudia; Droege, Thomas; Wang, Congyang; Glorius, Frank Chemistry - A European Journal, 2011 , vol. 17, # 22 p. 6052 - 6055

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Citation Number: 42

Abstract

Metal-catalyzed cross-coupling reactions are among the most important transformations in organic synthesis, allowing the efficient construction of complex structures from simpler, readily available building blocks.[1] Many applications in large and small-scale synthesis can be found in different areas such as agrochemicals, pharmaceuticals and supramolecular chemistry. Whereas the coupling of sp2-hybridized carbon atoms in either ...