Tetrahedron

Condensation of acyl chloride on sodium cyanate: preparation of acyl isocyanates

MZ Deng, P Caubere, JP Senet, S Lecolier

Index: Deng, M. Z.; Caubere, P.; Senet, J. P.; Lecolier, S. Tetrahedron, 1988 , vol. 44, # 19 p. 6079 - 6086

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Citation Number: 25

Abstract

The catalytic effects of various metal halides and solvents on the reaction of benzoyl chloride with sodium cyanate were studied. It has been found that SnCl4, and ZnCl2. catalyze the reaction to give the corresponding acyl isocyanates in good yields. The scope of the reaction was studied and a number of aroyl isocyanates and their derivatives were prepared. A few non aromatic isocyanates and their derivatives were also prepared.

 Related Synthetic Route

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Detail

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