e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Synthesis and reactions of imidates containing 1-adamantyl group
BI No, YL Zotov, EV Shishkin, DS Klimov
Index: No, B. I.; Zotov, Yu. L.; Shishkin, E. V.; Klimov, D. S. Russian Journal of General Chemistry, 2001 , vol. 71, # 11 p. 1807 - 1810 Zhurnal Obshchei Khimii, 2001 , vol. 71, # 11 p. 1911 - 1914
These compounds were prepared by a traditional version of the Pinner reaction [3]: The appropriate nitrile and alcohol were taken in equimolar amounts, and the reaction was performed in diethyl ether at 0oC. Shvekhgeimer et al. [2] took hydrogen chloride in a large excess. We reproduced these syntheses and found that the rate of formation of imidate hydrochlo- rides largely depends on the amount of hydrogen chloride taken into the reaction. However, even at full ...