Conformational studies of α-substituted ketones by nuclear magnetic resonance

TE Gough, WS Lin…

Index: Gough,T.E. et al. Canadian Journal of Chemistry, 1967 , vol. 45, p. 2529 - 2535

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Citation Number: 10

Abstract

The nuclear magnetic resonance spectra are reported for a series of α-substituted 3- pentanones. Magnetically nonequivalent methylene hydrogens are observed whenever the substituent group is diamagnetically anisotropic. The results are discussed in terms of the possible conformations of the molecules; the most stable conformations are those with the C= O bond essentially eclipsed by the terminal methyl groups.