Tetrahedron letters

Highly chemo-and stereoselective Fe-catalyzed alkenylation of organomanganese reagents

G Cahiez, S Marquais

Index: Cahiez, Gerard; Marquais, Sophie Tetrahedron Letters, 1996 , vol. 37, # 11 p. 1773 - 1776

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Citation Number: 93

Abstract

Organomanganese chlorides react with alkenyl iodides, bromides and chlorides in the presence of 3% Fe (acac) 3. The reaction takes place under very mild conditions (THF-NMP, rt, 1h) to afford the substituted olefin in excellent yields with a high stereo-and chemoselectivity. Thus an unprotected keto alkenyl chloride selectively gives the corresponding keto olefin. From a preparative point of view, this procedure is the first real ...