Expeditious synthesis of the marine natural products prepolycitrin A and polycitrins A and B through heck arylations

K Canto, R da Silva Ribeiro, AFP Biajoli…

Index: Canto, Karen; Da Silva Ribeiro, Rodrigo; Biajoli, Andre F. P.; Correia, Carlos Roque D. European Journal of Organic Chemistry, 2013 , # 35 p. 8004 - 8013

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Citation Number: 7

Abstract

Abstract New, efficient protocols for the syntheses of the marine natural products prepolycitrin A as well as polycitrins A and B were developed by employing the Heck– Matsuda arylation of maleic anhydride or dimethyl fumarate with aryldiazonium tetrafluoroborates. Both symmetrical and unsymmetrical 3, 4-diarylmaleic anhydrides were easily and effectively prepared. Efficient bromination reactions that employed ...