PdII??Catalysed C H Functionalisation of Indoles and Pyrroles Assisted by the Removable N??(2??Pyridyl) sulfonyl Group: C2??Alkenylation and Dehydrogenative …

A García??Rubia, B Urones…

Index: Garcia-Rubia, Alfonso; Urones, Beatriz; Arrayas, Ramon Gomez; Carretero, Juan Carlos Chemistry - A European Journal, 2010 , vol. 16, # 31 p. 9676 - 9685

Full Text: HTML

Citation Number: 112

Abstract

Abstract The easily installed and removed N-(2-pyridyl) sulfonyl group exerts complete C2 regiocontrol over the Pd II-catalysed C [BOND] H alkenylation of indoles and pyrroles, affording the corresponding products in good isolated yields (typically≥ 70%). A remarkable feature of this catalyst system is that it tolerates a wide variety of substituted alkenes, including conjugated electron-deficient alkenes, styrenes and 1, 3-dienes, as well as ...