Palladium??Catalyzed Asymmetric Hydrogenation of α??Acyloxy??1??arylethanones

…, N Butt, C Li, D Fan, Y Liu, W Zhang

Index: Chen, Jianzhong; Liu, Delong; Butt, Nicholas; Li, Chao; Fan, Dongyang; Liu, Yangang; Zhang, Wanbin Angewandte Chemie - International Edition, 2013 , vol. 52, # 44 p. 11632 - 11636 Angew. Chem., 2013 , vol. 125, # 44 p. 11846 - 11850,5

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Citation Number: 18

Abstract

Jianzhong Chen, Delong Liu, Nicholas Butt, Chao Li, Dongyang Fan, Yangang Liu, and Wanbin Zhang* α-Acyloxy-1-arylethanols, especially those possessing chiral centers, are a class of useful structural motifs commonly found in natural products and drug candidates.[1] They can serve as important intermediates for the preparation of many bioactive and medicinal molecules (Figure 1).[2] However, little attention has been focused on their ...