Tetrahedron Letters

Efficient dehydrative C–N bond formation using alcohols and amides in the presence of silica supported perchloric acid as a heterogeneous catalyst

B Das, PR Reddy, C Sudhakar, M Lingaiah

Index: Das, Biswanath; Reddy, Parigi Raghavendar; Sudhakar, Chithaluri; Lingaiah, Maram Tetrahedron Letters, 2011 , vol. 52, # 27 p. 3521 - 3522

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Citation Number: 11

Abstract

Abstract Silica supported perchloric acid has been utilized as an efficient heterogeneous recyclable catalyst for N-alkylation of amides (sulfonamides and carboxamides) using alcohols (primary and secondary aliphatic as well as benzylic). The products are formed in high yields within 2–3 h.