Abstract A series of hybrid molecules (7–9, 12, 13, and 14–18) consisting of chromans and pyrolidines or cyclic amines were prepared either by (3+ 2) cycloaddition of nitrostyrenes and azomethine ylide or by three component reactions of chromanyl aldehydes, acetylenes, and cyclic amines. All the synthesized compounds were evaluated against both avirulent (H37Ra) and virulent (H37Rv) strains of Mycobacterium tuberculosis. Out of all the ...
