Liebigs Annalen der Chemie

A new method for N??alkylation of imidazoles and benzimidazoles

B Pilarski

Index: Pilarski, Boguslaw Liebigs Annalen der Chemie, 1983 , # 6 p. 1078 - 1080

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Citation Number: 35

Abstract

In the new general method N-alkylation of imidat. oles and benzimidazoles occurs in the presence of alkaline reagents'.*). The reactions of imidazoles and benzimidazoles with an alkyl halide are commonly carried out in the pi-esence of a hydroxide of an alkali melal or alkaline earlh element 31435), sodium alkoxide or sodium amide with solvents such as ethanol, dioxane, toluene, r= l

~99%

~93%

~72%

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