Journal of heterocyclic chemistry

Synthesis of substituted 3??amino??4??cyano??1??oxo??1, 2, 5, 10??tetrahydroazepino [3, 4??b] indoles

R Troschütz, A Hoffmann

Index: Troschuetz, Reinhard; Hoffmann, Armin Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 5 p. 1431 - 1440

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Citation Number: 13

Abstract

Abstract The preparation of 3-amino-and 3-dialkylamino-4-cyanoazepino [3, 4-fc] indoles bearing substituents on the aromatic nucleus and N 10 is outlined. Starting from suitable substituted ethyl 3-formylindole-2-carboxy-latcs 2, condensation with malononitrile (3) and