Journal of medicinal chemistry

Derivatives of Fluorene. XXIII. 1 New Thiofluorenes Related to Metabolism of the Carcinogen N-2-Fluorenylacetamide

TL Fletcher, MJ Namkung, HL Pan

Index: Fletcher,T.L. et al. Journal of Medicinal Chemistry, 1967 , vol. 10, p. 936 - 941

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Citation Number: 13

Abstract

After deamination and reduction of the sulfoxide, nitro, and 9-oxo groups, we obtained an extremely small yield of 3-met hj-lt hio-Muorenamine and its?;-acetyl derivative (I) which had the same melting poilit and iiifr: md spectrum ab the compound, meti-tioned above, obtained by ldlikar, et al. 4 In addition, deamination of the compound obtained by hydrolysis of I (as recovered from the interaction of methionine and S-acetoxy-Fh.\ by I, otlil; ar, et~ 1.~) gave ...

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