A novel method for the separation of bis (α-hydroxyalkyl) phosphinic acid diastereoisomers via formation of novel cyclic phosphinic acids

B Kaboudin, H Haghighat…

Index: Kaboudin; Balakrishna Synthetic Communications, 2001 , vol. 31, # 18 p. 2773 - 2776

Full Text: HTML

Citation Number: 30

Abstract

The reaction of aromatic and aliphatic aldehydes with hypophosphorus acid under microwave irradiation was examined. The reaction gave a mixture of a racemic pair of bis (α- hydroxyalkyl) phosphinic acids and acetal derivatives from the corresponding bis (α-