Tetrahedron letters

Mild N-dealkylation of tertiary, benzylic amines with acid chlorides: Application to solid-phase chemistry

MW Miller, SF Vice, SW McCombie

Index: Miller, Michael W.; Vice, Susan F.; McCombie, Stuart W. Tetrahedron Letters, 1998 , vol. 39, # 21 p. 3429 - 3432

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Citation Number: 42

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... A mild, facile cleavage of appropriately substituted tertiary, benzylic amines with acid chlorides is described for both solution and solid phase. ... Leysen et al (ref. 4) stated that cleavage of the resin bound amines with chloroformates gave the corresponding cabamates (ie ...