e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Pyrazolopyrimidines as highly potent and selective, ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR): Optimization of the 1-substituent
KJ Curran, JC Verheijen, J Kaplan, DJ Richard…
Index: Bioorganic and Medicinal Chemistry Letters, , vol. 20, # 4 p. 1440 - 1444
... Please enable JavaScript to use all the features on this page. Bioorganic & Medicinal Chemistry Letters. Volume 20, Issue 4, 15 February 2010, Pages 1440–1444. ... a Chemical Sciences, Wyeth Research, 401 N. Middletown Rd, Pearl River, NY 10965, United States; ...
![tert-butyl 2-(1,4-dioxaspiro[4.5]decan-8-yl)hydrazinecarboxylate Structure](https://image.chemsrc.com/caspic/115/1144080-27-2.png)
![1,4-dioxaspiro[4.5]decan-8-ylhydrazine Structure](https://image.chemsrc.com/caspic/039/1144080-29-4.png)
![4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(1,4-dioxaspiro[4.5]decan-8-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl)aniline Structure](https://image.chemsrc.com/caspic/329/1144068-84-7.png)
