Oxidative Amidation of Aldehydes and Alcohols with Primary Amines Catalyzed by KI??TBHP

…, CU Maheswari, M Venkateshwar…

Index: Rajender Reddy; Uma Maheswari; Venkateshwar; Lakshmi Kantam European Journal of Organic Chemistry, 2008 , # 21 p. 3619 - 3622

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Citation Number: 59

Abstract

Abstract Oxidative amidation of aldehydes and alcohols with amines to afford the corresponding amides in excellent yields and ee values over 98% is achieved by using a catalytic amount of KI in combination with TBHP as the external oxidant. This method avoids the use of expensive and/or air-sensitive reagents.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)