Synthesis and antioxygenic activities of seabuckthorn flavone-3-ols and analogs

N Pandurangan, C Bose, A Banerji

Index: Pandurangan; Bose, Chinchu; Banerji Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 18 p. 5328 - 5330

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Citation Number: 19

Abstract

A practical synthesis of polyhydroxy-and regiospecifically methylated flavone-3-ols which are components of commercial 'seabuckthorn flavone'has been achieved by modified Algar– Flynn–Oyamada method. Antioxidant activities of seabuckthorn extracts, isolated products and a number of flavone-3-ols have been determined. Structure–activity relationships have been discussed. Amongst the compounds tested, gallic acid, which is also present in ...