The Journal of Organic Chemistry

Reaction of diethyl phosphonate with methyl and ethyl Grignard reagents

HR Hays

Index: Hays,H.R. Journal of Organic Chemistry, 1968 , vol. 33, p. 3690 - 3694

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Citation Number: 99

Abstract

The reaction of diethyl phosphonate with methyl and ethyl Grignard reagents has been investigated. Chemical and physical evidence suggest that the intermediate (I) $ not a diethoxyphosphmylmagnesium halide [(RO) r P (-. O) MgX] but is a trivalent phosphorus species [(R0) zPOMgXI. The latter undergoes rapid substitution with methyl Grignard reagent at 25" to give the halomagnesium dimethyl-and diethylphosphinites (RsPOMgX), ...