Synthesis of semisynthetic dipeptides using N-carboxyanhydrides and chiral induction on Raney nickel. A method practical for large scale

TJ Blacklock, RF Shuman, JW Butcher…

Index: Journal of Organic Chemistry, , vol. 53, # 4 p. 836 - 844

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Citation Number: 58

Abstract

... quantities via N-carboxyanhydride (NCA) chemistry in water after first mastering the effects of the countercation and of the organic cosolvent during ... See: Greenstein, JP; Winitz, M. Chemistry of the Amino Acids; Wiley: New York, 1961; p 915 ... 21) Schallenberg, EE; Calvin, M. J. Am ...