Biomimetic oxidation of aromatic xenobiotics: synthesis of the phenolic metabolites from the anti-HIV drug efavirenz

R Wanke, DA Novais, SG Harjivan…

Index: Organic and Biomolecular Chemistry, , vol. 10, # 23 p. 4554 - 4561

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Citation Number: 3

Abstract

... Chem., 2012, 10, 4554-4561 Show Compounds Show Chemical Terms. ... These consisted of the use of an AcCN–AcOEt (1 : 1) solution of EFV, 10 mol% of Fe II ... steric hindrance in the vicinity of the ring fusion, that namely inhibited the activity of bulky organic peroxides, such as t ...