4, 4-Dimethyl-1, 2, 3, 4-tetrahydroquinoline-based PPARα/γ agonists. Part I: Synthesis and pharmacological evaluation

C Parmenon, J Guillard, DH Caignard…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 18, # 5 p. 1617 - 1622

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Citation Number: 30

Abstract

... Please enable JavaScript to use all the features on this page. Bioorganic & Medicinal Chemistry Letters. ... The final ester–ether was then obtained in 3 steps under previous conditions in 98% ee and 60% chemical yield (Scheme 7). 13. ...