Retinoids, natural and synthetic analogues of vitamin A, play a major role in controlling cell proliferation and differentiation. These properties confer on this class of substances a high potential for the treatment of various hyperproliferative diseases. 2 all-trans-Retinoic acid (AtRA), 13-cis-retinoic acid, and synthetic analogues are widely used by both the topical and oral routes of administration in the management of dermatological diseases such as acne, ...
