e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Treatment of atherosclerosis in apolipoprotein E-deficient mice with 4-(3′-bromobenzoyl)-6, 7-dimethoxyquinazoline (WHI-P164), a potent inhibitor of triglyceride …
…, XP Liu, CL Chen, FM Uckun
Index: Trieu, Vuong N.; Liu, Xing-Ping; Chen, Chun-Lin; Uckun, Fatih M. Journal of Cardiovascular Pharmacology, 2000 , vol. 35, # 2 p. 179 - 188
Abstract We identified a novel organic compound, 4-(3′-bromobenzoyl)-6, 7- dimethoxyquinazoline (compound WHI-P164), as a potent inhibitor of triglyceride (TG) synthesis. In an in vitro model of lipid synthesis, WHI-P164 (but not any one of the three structurally similar control dimethoxyquinazoline compounds) inhibited the accumulation of TG-rich intracellular lipid droplets in Caco-2 human intestinal cells in a concentration- ...
