Nonpeptide angiotensin II receptor antagonists: the discovery of a series of N-(biphenylylmethyl) imidazoles as potent, orally active antihypertensives

DJ Carini, JV Duncia, PE Aldrich, AT Chiu…

Index: Journal of Medicinal Chemistry, , vol. 34, # 8 p. 2525 - 2547

Full Text: HTML

Citation Number: 452

Abstract

... Medical Products Department, Pharmaceuticals Division, Experimental Station, E. I. du Pont de Nemours & Company, Inc., Wilmington, Delaware 19880-0402. Received December 12, 1990 ... Page 2. 2526 Journal of Medicinal Chemistry, 1991, Vol. 34, No. 8 ...

 Related Synthetic Route

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%