Use of Conformationally Restricted Benzamidines as Arginine Surrogates in the Design of Platelet GPIIb-IIIa Receptor Antagonists 1

DJ Sall, AE Arfsten, JA Bastian…

Index: Journal of Medicinal Chemistry, , vol. 40, # 18 p. 2843 - 2857

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Citation Number: 29

Abstract

... Journal of Medicinal Chemistry. ... More recently, the pharmaceutical strategy has focused on the design of small molecule, orally active antagonists for the chronic and/or prophylactic treatment of arterial thrombosis. ...