Discovery of a novel non-steroidal GR antagonist with in vivo efficacy in the olanzapine-induced weight gain model in the rat

…, J Sutton, M Sajad, E O'Connor, S Ahmed…

Index: Hunt, Hazel J.; Ray, Nicholas C.; Hynd, George; Sutton, Jon; Sajad, Mohammed; O'Connor, Elizabeth; Ahmed, Shahadat; Lockey, Peter; Daly, Steve; Buckley, Gerry; Clark, Robin D.; Roe, Robert; Blasey, Christine; Belanoff, Joe Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 24 p. 7376 - 7380

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Citation Number: 4

Abstract

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... There might be a brief outage due to maintenance of ScienceDirect on December 20 between 12:00 am EST ( 5:00 am GMT) and 12:00 pm EST (5:00 pm GMT) - it is not expected to last more than 10 minutes. ... We report the optimization of a series of non-steroidal GR antagonists that ...