A Mild and Versatile Method for Palladium??Catalyzed Cross??Coupling of Aryl Halides in Water and Surfactants

…, G Cerichelli, M Chiarini, M Correa…

Index: Arcadi, Antonio; Cerichelli, Giorgio; Chiarini, Marco; Correa, Mariano; Zorzan, Daniel European Journal of Organic Chemistry, 2003 , # 20 p. 4080 - 4086

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Citation Number: 79

Abstract

Abstract Various aqueous surfactants proved to be excellent media for carrying out palladium-catalyzed Suzuki− Miyaura cross-coupling reactions under mild conditions. The dehalogenation side reaction, which is usually a drawback with the aqueous protocol, was not observed. The concentration of the surfactant in water played a pivotal role for the reaction outcome. Smooth cross-coupling of iodoanisole and a variety of aryl bromides, ...