An alternative synthesis of tiopinac

TC Thurber, A Prince, O Halpern

Index: Thurber, T. Craig; Prince, Anthony; Halpern, Otto Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 961 - 965

Full Text: HTML

Citation Number: 7

Abstract

Jul-Aug 1982 An Alternative Synthesis of Tiopinac T. Craig Thurber*, Anthony Prince and Otto Halpern Contribution Number 567, Development Research Laboratory, Institute of Organic Chemistry, Syntex Research, 3401 Hillview Avenue, Palo Alto, CA 94304 Received September 11, 1981 Tiopinac (1) [6, 11-dihydro-l l-oxodibenzo[b,e]thiepin-3-acetic acid, (1)] has shown a high degree of antiin- flammatory activity and a low incidence of side effects in animals ...