TEMPO-mediated oxidation of primary alcohols to carboxylic acids by exploitation of ethers in an aqueous-organic biphase system

…, LJ Ma, H Kawafuchi, T Okihara, T Inokuchi

Index: Mei, Zhen-Wu; Ma, Li-Jian; Kawafuchi, Hiroyuki; Okihara, Takumi; Inokuchi, Tsutomu Bulletin of the Chemical Society of Japan, 2009 , vol. 82, # 8 p. 1000 - 1002

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Citation Number: 6

Abstract

Expeditious and benign methods for primary alcohol–carboxylic acid conversions with TEMPO were developed in a biphasic system composed of a slightly miscible ether (THP) and aqueous layer. Easily available co-oxidants such as Py· HBr 3, Bu 4 NBr 3, and electrooxidation were successfully applied to generate N-oxoammonium species as a recyclable catalyst.