Tetrahedron

Studies on organophosphorus compounds—XLI: Formation of 3-pyrazoline-5-thione disulfides from 3, 5-pyrazolidinediones. C-alkylation of 3, 5-pyrazolidinediones

S Scheibye, AA El-Barbary, SO Lawesson, H Fritz…

Index: Scheibye,S.; El-Barbary,A.A. Tetrahedron, 1982 , vol. 38, p. 3753

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Citation Number: 46

Abstract

4-Substituted-1, 2-diphenyl-3, 5-pyrazolidinediones (Phenylbutazone analogous) 1a–d react with 2, 4-bi-(4-methoxyphenyl)-1, 3, 2, 4-dithiadiphosphetane 2, 4-difulside (Lawesson Reagent (LR) with formation of the corresponding 3, 3′-dithiobis (1, 2-dihydro-3H-pyrazole- 5-thione)'s 2a–d. When the 4-substituent contains a sulfoxide group this is deoxygenated to the sulfide by LR at room tmeperature. 1-Phthalazinone-4-thione, 1, 4-phthalazine- ...