Tetrahedron

Practical synthesis of amides from alkynyl bromides, amines, and water

ZW Chen, HF Jiang, XY Pan, ZJ He

Index: Chen, Zheng-Wang; Jiang, Huan-Feng; Pan, Xiao-Yan; He, Zai-Jun Tetrahedron, 2011 , vol. 67, # 33 p. 5920 - 5927

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Citation Number: 41

Abstract

A general and efficient method for the synthesis of a wide range of amides is described here. The reactions were conducted under convenient conditions and provided secondary and tertiary amides in moderate to excellent yields. A variety of amines and substituted alkynyl bromides were used to investigate the scope of the reactions.