Synthesis of 5??, 6??, 7??and 18??mono??13C??labelled retinals

…, GKT Lam, AJM Peters, J Lugtenburg

Index: Courtin, J. M. L.; 't Lam, G. K.; Peters, A. J. M.; Lugtenburg, J. Recueil des Travaux Chimiques des Pays-Bas, 1985 , vol. 104, # 11 p. 281 - 288

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Citation Number: 11

Abstract

Abstract Four retinals labelled at positions 5, 6, 7 and 18 with 13 C were obtained via simple schemes involving only a few steps with> 98% chemical purity and 92% 13 C incorporation.(5-13 C) Retinal was obtained in 26% yield from K 13 CN.(6-13 C)-and (7-13 C) Retinal were obtained in 37% yield from (2-13 C)-and (1-13 C) acetonitrile, respectively, while (18-13 C) retinal was obtained in 8 steps and 4% yield starting from 13 CH 3 I. Their ...

~80%

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