Tetrahedron letters

Mechanistic and synthetic aspects of the acid-catalysed hydrolysis of 2, 2-dimethoxy-3, 4-dihydropyrans into 3, 4-dihydro-α-pyrones and δ-keto esters

JW Scheeren, CG Bakker, R Peperzak, RJF Nivard

Index: Scheeren, J. W.; Bakker, C. G.; Peperzak, R.; Nivard, R. J. F. Tetrahedron Letters, 1987 , vol. 28, # 16 p. 1821 - 1824

Full Text: HTML

Citation Number: 1

Abstract

Acid-catalysed hydrolysis of 2,2-dimethoxy-3,4-dihydropyrans ( ) yields mixtures of δ-keto esters ( ) and 3,4-dihydro-α-pyrones ( ). The amount of increases with increasing alkyl substitution in the 3-, 5- and 6-position of and when the hydrolysis is carried out in a two-phases system ...