e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Design, synthesis and in vitro antibacterial/antifungal evaluation of novel 1-ethyl-6-fluoro-1, 4-dihydro-4-oxo-7 (1-piperazinyl) quinoline-3-carboxylic acid derivatives
A series of 1-ethyl-6-fluoro-1, 4-dihydro-4-oxo-7 (1-piperazinyl) quinoline-3-carboxylic acid (norfloxacin) derivatives were prepared according to the principle of combinating bioactive substructures and tested for their activities against five plant pathogenic bacteria and three fungi in vitro. The preliminary bioassays indicated that almost all synthesized target compounds retained the antibacterial activities of norfloxacin and had some antifungal ...
