Journal of pharmaceutical sciences

Methyl??substituted tyrosines and related compounds as potential anticancer agents

EC Jorgensen, RA Wiley

Index: Jorgensen,E.C.; Wiley,R.A. Journal of Pharmaceutical Sciences, 1963 , vol. 52, p. 122 - 125

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Citation Number: 5

Abstract

Abstract 3, 5-Dimethyl-DL-tyrosine, 3-methyl-DL-tyrosine, 3-methyl-5-iodo-DL-tyrosine, as well as synthetic intermediates and derivatives of these, have been prepared for study of anticancer activity. Preliminary tests on two members of the series against experimental tumors in mice showed a slight inhibition of tumor growth.